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bibliographic references and footnotes for the English paperback edition of How Not to Die With True High-Dose Vitamin D Therapy

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bibliographic references and footnotes for the English paperback edition of How Not to Die With True High-Dose Vitamin D Therapy

1. Coelho MP. Chegar novo a velho, medicina do futuro. 2016. Page 134

2. Video: https://www.youtube.com/watch?v=7OzP77HtR0Q at 2 minutes and 40 seconds.

3. Chowdhury R, Kunutsor S, Vitezova A, et al. Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies.

The BMJ. 2014;348:g1903. doi:10.1136/bmj.g1903. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972416/

4. Image: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897595/figure/F8/

5. Image: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897595/figure/F9/

6. Finamor DC, Sinigaglia-coimbra R, Neves LC, et al. A pilot study assessing the effect of prolonged administration of high daily doses of vitamin D on the clinical course of vitiligo and psoriasis. Dermatoendocrinol. 2013;5(1):222-34. https://www.ncbi.nlm.nih.gov/pubmed/24494059

7. Pilz S, Dobnig H, Fischer JE, et al. Low vitamin d levels predict stroke in patients referred to coronary angiography. Stroke. 2008;39(9):2611-3. https://www.ncbi.nlm.nih.gov/pubmed/18635847

8. Garland CF, Comstock GW, Garland FC, Helsing KJ, Shaw EK, Gorham ED. Serum 25-hydroxyvitamin D and colon cancer: eight-year prospective study. Lancet. 1989;2(8673):1176-8. https://www.ncbi.nlm.nih.gov/pubmed/2572900

9. Lowe LC, Guy M, Mansi JL, et al. Plasma 25-hydroxy vitamin D concentrations, vitamin D receptor genotype and breast cancer risk in a UK Caucasian population. Eur J Cancer. 2005;41(8):1164-9. https://www.ncbi.nlm.nih.gov/pubmed/15911240

10. Compilation of studies demonstrating the positive effects of vitamin D on cancer: http://www1.grassrootshealth.net/breast-cancer-studies. Holick MF, Chen TC. Vitamin D deficiency: a worldwide problem with health consequences. Am J Clin Nutr. 2008;87(4):1080S-6S. https://www.ncbi.nlm.nih.gov/pubmed/18400738

12. Naeem Z. Vitamin D Deficiency- An Ignored Epidemic. International Journal of Health Sciences. 2010;4(1):V-VI. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068797/

13. Norman AW. From vitamin D to hormone D: fundamentals of the vitamin D endocrine system essential for good health. Am J Clin Nutr. 2008;88(2):491S-499S. https://www.ncbi.nlm.nih.gov/pubmed/18689389.

14. Herrmann W, Obeid R. Causes and Early Diagnosis of Vitamin B12 Deficiency. Deutsches Ärzteblatt International. 2008;105(40):680-685. doi:10.3238/arztebl.2008.0680.

15. Holick MF, Chen TC. Vitamin D deficiency: a worldwide problem with health consequences. Am J Clin Nutr. 2008;87(4):1080S-6S. https://www.ncbi.nlm.nih.gov/pubmed/18400738

16. Naeem Z. Vitamin D Deficiency- An Ignored Epidemic. International Journal of Health Sciences. 2010;4(1):V-VI. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068797/

17. They even gave a name to the science of name giving: onomatology.

18. Christakos S, Ajibade DV, Dhawan P, Fechner AJ, Mady LJ. Vitamin D: Metabolism. Endocrinology and metabolism clinics of North America. 2010;39(2):243-253. doi:10.1016/j.ecl.2010.02.002. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879391/

19. Each of these four chemicals is also known by many different names. You don’t need to memorize them all, and diagram 2 helps us undo any confusion.

20. Article: https://www.nationalmssociety.org/What-is-MS/MS-FAQ-s#question-Is-MS-fatal

21. Video in Portuguese: https://www.youtube.com/watch?v=7OzP77HtR0Q from 2 minutes and 40 seconds

22. Video, in Portuguese: http://sic.sapo.pt/Programas/altadefinicao/videos/2017-03-19-Alta

23. Video, in Portuguese: http://sic.sapo.pt/Programas/altadefinicao/videos/2015-05-23-Bernardo-Pinto-Coelho-em-Alta-Definicao

24. Video, in English with Portuguese subtitles: https://www.youtube.com/watch?v=Hh8k32VsxLA

25. Video, in Portuguese: https://www.youtube.com/watch?v=hOfO29rL-gI

26. Article: http://www.auburn.edu/academic/forestry_wildlife/fire/combustion.htm

27. Article: https://www.wired.com/2010/11/1110mars-climate-observer-report/

28. Armas LA, Hollis BW, Heaney RP. Vitamin D2 is much less effective than vitamin D3 in humans. J Clin Endocrinol Metab. 2004; 89 (11): 5387-91. https://www.ncbi.nlm.nih.gov/pubmed/15531486

29. Article: https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/

30. Tripković L, Lambert M, K Hart et al. Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysis. The American Journal of Clinical Nutrition.2012; 95 (6): 1357-1364. doi: 10.3945 / ajcn.111.031070. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349454/

31. Lipkie TE, Ferruzzi MG, Weaver CM. Low bioaccessibility of vitamin D2 from yeast-fortified bread compared to crystalline D2 bread and D3 from fluid milks. Food Funct. 2016;7(11):4589-4596. https://www.ncbi.nlm.nih.gov/pubmed/27734047

32. Keegan R-H, Lu Z, Bogusz JM, Williams JE, Holick MF. Vitamin D photobiology of mushrooms and its bioavailability in humans. Dermato-Endocrinology.2013; 5 (1): 165-176. doi: 10.4161 / derm.23321. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897585/

33. Article: https://dietarysupplementdatabase.usda.nih.gov/ingredient_calculator/equation.php

34. Domene AC. Multiple Sclerosis and (lots of) Vitamin D: My eight-year Treatment with The Coimbra Protocol for Autoimmune Diseases. Amazon Digital Services LLC. 2016. Page 16.

35. Goldenberg MM. Multiple Sclerosis Review. Pharmacy and Therapeutics.2012; 37 (3): 175-184. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351877/

36. Sieper J, Braun J, M Rudwaleit Boonen A Zink A. ankylosing spondylitis: an overview. Annals of the Rheumatic Diseases.2002; 61 (Suppl 3): iii18-III8. doi: 10.1136 / ard.61.suppl_3.iii8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1766729/

37. Hathcock JN, Shao A, Vieth R, Heaney R. Risk assessment for vitamin D. Am J Clin Nutr. 2007;85(1):6-18. https://www.ncbi.nlm.nih.gov/pubmed/17209171

38. Article: https://www.vitamindcouncil.org/about-vitamin-d/am-i-getting-too-much-vitamin-d/

39. Vieth R. Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety. Am J Clin Nutr. 1999;69(5):842-56. https://www.ncbi.nlm.nih.gov/pubmed/10232622

40. Article: https://www.vitamindcouncil.org/about-vitamin-d/how-do-i-get-the-vitamin-d-my-body-needs/

41. Matsuoka LY, Ide L, Wortsman J, Maclaughlin JA, Holick MF. Sunscreens suppress cutaneous vitamin D3 synthesis. J Clin Endocrinol Metab. 1987;64(6):1165-8. https://www.ncbi.nlm.nih.gov/pubmed/3033008

42. Holick M. “Photobiology of Vitamin D” Vitamin D: Second Edition, 2005.

43. Article: https://www.vitamindcouncil.org/about-vitamin-d/how-do-i-get-the-vitamin-d-my-body-needs/

44. Detailed information on the amounts of vitamin D3 and D2 present in various foods is available in Appendix A.

45. Article: http://www.thisisms.com/forum/coimbra-high-dose-vitamin-d-protocol-f57/topic27182.html 46. Article: https://www.livestrong.com/article/537905-can-drinking-too-much-water-cause-low-potassium/

47. Balcı AK, Koksal O, Kose A, et al. General characteristics of patients with electrolyte imbalance admitted to emergency department. World Journal of Emergency Medicine. 2013;4(2):113-116. doi:10.5847/wjem.j.issn.1920-8642.2013.02.005. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129840/

48. Weglicki W, Quamme G, Tucker K, Haigney M, Resnick L. Potassium, magnesium, and electrolyte imbalance and complications in disease management. Clin Exp Hypertens. 2005;27(1):95-112. https://www.ncbi.nlm.nih.gov/pubmed/15773233

49. Ritter CS, Armbrecht HJ, Slatopolsky E, Brown AJ. 25-Hydroxyvitamin D(3) suppresses PTH synthesis and secretion by bovine parathyroid cells. Kidney Int. 2006;70(4):654-9. https://www.ncbi.nlm.nih.gov/pubmed/16807549

50. Friedl C, Zitt E. Vitamin D prohormone in the treatment of secondary hyperparathyroidism in patients with chronic kidney disease. Int J Nephrol Renovasc Dis. 2017;10:109-122. https://www.ncbi.nlm.nih.gov/pubmed/28546765

51. Lotito A, Teramoto M, Cheung M, Becker K, Sukumar D. Serum Parathyroid Hormone Responses to Vitamin D Supplementation in Overweight/Obese Adults: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Nutrients. 2017;9(3):241. doi:10.3390/nu9030241. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372904/

52. Abrams SA, Hawthorne KM, Chen Z. Supplementation with 1000 IU vitamin D/d leads to parathyroid hormone suppression, but not increased fractional calcium absorption, in 4-8-y-old children: a double-blind randomized controlled trial. Am J Clin Nutr. 2013;97(1):217-23. https://www.ncbi.nlm.nih.gov/pubmed/23151536

53. Tardelli VS, Lago MPPD, Silveira DXD, Fidalgo TM. Vitamin D and alcohol: A review of the current literature. Psychiatry Res. 2017;248:83-86. http://www.psy-journal.com/article/S0165-1781(16)30706-5/fulltext 54. Epstein M. Alcohol's impact on kidney function. Alcohol Health Res World. 1997;21(1):84-92.Epstein M. Alcohol's impact on kidney function. Alcohol Health Res World. 1997;21(1):84-92. https://www.ncbi.nlm.nih.gov/pubmed/15706766

55. Sampson HW. Alcohol's harmful effects on bone. Alcohol Health Res World. 1998;22(3):190-4. https://www.ncbi.nlm.nih.gov/pubmed/15706795

56. Szabo G, Mandrekar P. Focus On: Alcohol and the Liver. Alcohol Research & Health. 2010;33(1-2):87-96. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3860520/

57. Zahr NM, Pfefferbaum A. Alcohol's Effects on the Brain: Neuroimaging Results in Humans and Animal Models. Alcohol Res. 2017;38(2):183-206. https://www.ncbi.nlm.nih.gov/pubmed/28988573

58. Tada A. Psychological effects of exercise on community-dwelling older adults. Clin Interv Aging. 2018;13:271-276. https://www.ncbi.nlm.nih.gov/pubmed/29483773

59. Blumenthal JA, Babyak MA, Moore KA, et al. Effects of exercise training on older patients with major depression. Arch Intern Med. 1999;159(19):2349-56. https://www.ncbi.nlm.nih.gov/pubmed/10547175

60. Lamina S, Agbanusi E, Nwacha RC. Effects of Aerobic Exercise in the Management of Erectile Dysfunction: A Meta Analysis Study on Randomized Controlled Trials. Ethiopian Journal of Health Sciences. 2011;21(3):195-201. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275865/

61. Silva AB, Sousa N, Azevedo LF, Martins C. Physical activity and exercise for erectile dysfunction: systematic review and meta-analysis. Br J Sports Med. 2017;51(19):1419-1424. https://www.ncbi.nlm.nih.gov/pubmed/27707739

62. Buchner DM, Beresford SA, Larson EB, Lacroix AZ, Wagner EH. Effects of physical activity on health status in older adults. II. Intervention studies. Annu Rev Public Health. 1992; 13:469-88. https://www.ncbi.nlm.nih.gov/pubmed/1599599/

63. Mcmillan LB, Zengin A, Ebeling PR, Scott D. Prescribing Physical Activity for the Prevention and Treatment of Osteoporosis in Older Adults. Healthcare (Basel). 2017;5(4) https://www.ncbi.nlm.nih.gov/pubmed/29113119

64. Hinton PS, Nigh P, Thyfault J. Effectiveness of resistance training or jumping-exercise to increase bone mineral density in men with low bone mass: A 12-month randomized, clinical trial. Bone. 2015;79:203-12. https://www.ncbi.nlm.nih.gov/pubmed/26092649

65. Zhao R, Zhao M, Zhang L. Efficiency of jumping exercise in improving bone mineral density among premenopausal women: a meta-analysis. Sports Med. 2014;44(10):1393-402. https://www.ncbi.nlm.nih.gov/pubmed/24981245

66. Paillard T. [Exercise and bone mineral density in old subjects: theorical and practical implications]. Geriatr Psychol Neuropsychiatr Vieil. 2014;12(3):267-73. https://www.ncbi.nlm.nih.gov/pubmed/25245313

67. Watson SL, Weeks BK, Weis LJ, Horan SA, Beck BR. Heavy resistance training is safe and improves bone, function, and stature in postmenopausal women with low to very low bone mass: novel early findings from the LIFTMOR trial. Osteoporos Int. 2015;26(12):2889-94. https://www.ncbi.nlm.nih.gov/pubmed/26243363/

68. Brot C, Jorgensen NR, Sorensen OH. The influence of smoking on vitamin D status and calcium metabolism. Eur J Clin Nutr. 1999;53(12):920-6. https://www.ncbi.nlm.nih.gov/pubmed/10602348

69. Ren W, Gu Y, Zhu L, et al. The effect of cigarette smoking on vitamin D level and depression in male patients with acute ischemic stroke. Compr Psychiatry. 2016;65:9-14. https://www.ncbi.nlm.nih.gov/pubmed/26773985

70. Coelho MP. Chegar novo a velho, medicina do futuro. 2016. Página 134

71. Yagnik D, Serafin V, J shah A. Antimicrobial activity of apple cider vinegar against Escherichia coli, Staphylococcus aureus and Candida albicans; downregulating cytokine and microbial protein expression. Sci Rep. 2018;8(1):1732. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788933/

72. Trill J, Simpson C, Webley F, et al. Uva-ursi extract and ibuprofen as alternative treatments of adult female urinary tract infection (ATAFUTI): study protocol for a randomised controlled trial. Trials. 2017;18(1):421. https://www.ncbi.nlm.nih.gov/pubmed/28886751

73. Hisano M, Bruschini H, Nicodemo AC, Srougi M. Cranberries and lower urinary tract infection prevention. Clinics. 2012;67(6):661-667. doi:10.6061/clinics/2012(06)18. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370320/

74. Francino MP. Antibiotics and the Human Gut Microbiome: Dysbioses and Accumulation of Resistances. Frontiers in Microbiology. 2015;6:1543. doi:10.3389/fmicb.2015.01543. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709861/

75. Coimbra CG, Junqueira VB. High doses of riboflavin and the elimination of dietary red meat promote the recovery of some motor functions in Parkinson's disease patients. Braz J Med Biol Res 2003; 36 (10). 1409-17. https://www.ncbi.nlm.nih.gov/pubmed/14502375

76. Anderson BB, Scattoni M, Perry GM, et al. Is the flavin-deficient red blood cell common in Maremma, Italy, an important defense against malaria in this area? American Journal of Human Genetics.1994; 55 (5): 975-980. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1918332/

77. Marashly ET, Bohlega SA. Riboflavin Has Neuroprotective Potential: Focus on Parkinson's Disease and Migraine. Front Neurol. 2017; 8: 333. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517396/

78. Adiloğlu AK Gönülateş N, M Isler, Senol A. [The effect of kefir consumption on human immune system: to study cytokine]. Mikrobiyol Bul. 2013; 47 (2): 273-81. https://www.ncbi.nlm.nih.gov/pubmed/23621727

79. Maresz K. Calcium Proper Use: Vitamin K2 as a Promoter of Bone and Cardiovascular Health. Integrative Medicine: A Clinician's Journal. 2015; 14 (1): 34-39. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566462/

80. JT Bowles. The Miraculous Results of Extremely High Doses of the Sunshine Hormone Vitamin D3 My Experiment with Huge doses of D3 from 25,000 to 50,000 to 100,000 Iu a Day Over 1 Year Period. CreateSpace; 2013.

81. Rabbit MP. Again reach old medicine of the future. 2016.

82. The Crescenti, Puiggròs F Colomé A, et al. [Antiurolithiasic effect of a mixture of Herniaria glabra plant, Agropyron repens, Equisetum arvense and Sambucus nigra (Herbensurina®) in the prevention of nephrolithiasis Experimentally induced in rats]. Arch Esp Urol. 2015; 68 (10): 739-49. https://www.ncbi.nlm.nih.gov/pubmed/26634575

83. Composition: (1) Herniaria glabra L. — whole plant — 1 gram per sachet. (2) Agropyron repens (L.) P. Beauv. — rhizome — 0.25 gram per sachet. (3) Equisetum arvense L. (Horsetail) — sterile stems — 0.15 grams per sachet. (4) Sambucus nigra L. — flower — 0.1 grams per sachet.

84. Personal communication during a consultation.

85. Bonnar J. Coagulation effects of oral contraception. Am J Obstet Gynecol. 1987; 157 (4 Pt 2): 1042-8. https://www.ncbi.nlm.nih.gov/pubmed/2960241

86. Article: https://www.sharecare.com/health/blood-basics/how-many-white-blood-cells

87. Article: https://www.healthline.com/health/how-much-blood-in-human-body

88. Article: https://www.vitamindcouncil.org/gene-expression-and-vitamin-d-whats-the-link/

89. The Nezhad-Hossein, Spira A, Holick MF. Influence of Vitamin D Status and Vitamin D3 Supplementation on Genome Wide Expression of White Blood Cells: A Randomized Double-Blind Clinical Trial. M Campbell, ed. PLoSONE.2013; 8 (3): e58725. doi: 10.1371 / journal.pone.0058725.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604145/

90. Prietl B, G Treiber, Pieber TR Amrein K. Vitamin D and Immune Function. Nutrients.2013; 5 (7): 2502-2521. doi: 10.3390 / nu5072502. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738984/

91. ES Chambers, Hawrylowicz CM. The impact of vitamin D on regulatory T cells. Curr Allergy Asthma Rep 2011; 11 (1):. 29-36. https://www.ncbi.nlm.nih.gov/pubmed/21104171

92. Sigmundsdottir H, J Pan, Debes GF, et al. DCs metabolize sunlight-induced vitamin D3 to 'program' T cell attraction to the epidermal chemokine CCL27. Nat Immunol. 2007; 8 (3): 285-93. https://www.ncbi.nlm.nih.gov/pubmed/17259988

93. Pillay J, Den Braber R, Vrisekoop N, et al. In vivo labeling with 2H2 reveals the lifespan of human neutrophil 5.4 hours. Blood. 2010; 116 (4): 625-7. http://www.bloodjournal.org/content/116/4/625?ijkey=1a3c177de0b39ae4c1ec8754e0b3c71cd72451d5 94. Cvetanovich GL, Hafler DA. Regulatory T Cells in Human Autoimmune Diseases. Current Opinion in Immunology. 2010; 22 (6): 753-760. doi: 10.1016 / j.coi.2010.08.012. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997859/

95. Lys K Kuzawińska O-Bałkowiec Iskra E. Tumor necrosis factor inhibitors — state of knowledge. Archives of Medical Science:AMS.2014; 10 (6): 1175-1185. doi: 10.5114 / aoms.2014.47827. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296073/

96. Article: http://www.news.med.br/p/saude/222530/oms+divulga+as+dez+principais+causas+de+morte+no+mundo.htm 97. Sharma RK, Sharma RK, Voelker DJ, et al. Cardiac risk stratification: Role of the coronary calcium score. Vascular Health and Risk Management.2010; 6: 603-611. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922321/

98. Maresz K. Calcium Proper Use: Vitamin K2 as a Promoter of Bone and Cardiovascular Health. Integrative Medicine: A Clinician's Journal. 2015; 14 (1): 34-39. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566462/

99. Rheaume-Bleue K. Vitamin K2 and the Calcium Paradox: How a Little-Known Vitamin Could Save Your Life. Harper; 2013. page 39

100. Lhermusier T, Chap H Payrastre B. Platelet membrane phospholipid asymmetry: from the characterization of the scramblase activity to the identification of an essential protein mutated in Scott syndrome. J Thromb Haemost. 2011; 9 (10): 1883-91. https://www.ncbi.nlm.nih.gov/pubmed/21958383

101. Haque JA, McDonald MG Kulman JD, Rettie AE. The cellular system is quantitation of vitamin K cycle activity: effects on structure-activity vitamin K warfarin metabolites by antagonism. Blood.2014; 123 (4): 582-589. doi: 10.1182 / blood-2013-05-505123. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901071/

102. Mikaelsson ME (1991) The Role of Calcium in Coagulation and Anticoagulation. In: Sibinga CTS, Das PC, Mannucci PM (eds) Coagulation and Blood Transfusion. Developments in Hematology and Immunology, vol 26. Springer, Boston, MA

103. It’s noteworthy that milk and milk products such as cheese, are contraindicated in a protocol with high doses of vitamin D due to their high calcium content.

104. Tsukamoto Y, M Ichise , Kakuda H, Yamaguchi M. Intake of fermented soybean (natto) Increases circulating vitamin K2 (menaquinone-7) and gamma-carboxylated osteocalcin concentration in Normal Individuals. J Bone Miner Metab. 2000; 18 (4): 216-22. https://www.ncbi.nlm.nih.gov/pubmed/10874601

105. Article: https://pubchem.ncbi.nlm.nih.gov/compound/octane

106. Article: https://pubchem.ncbi.nlm.nih.gov/compound/ethane

107. Article: https://pubchem.ncbi.nlm.nih.gov/compound/benzene

108. Sato T, LJ Schurgers, Uenishi K. Comparison of menaquinone-4 and menaquinone-7 bioavailability in healthy women. J Nutr 2012; 11: 93. https://www.ncbi.nlm.nih.gov/pubmed/23140417

109. A fictitious vitamin.

110. This specific supplement also contains vitamin K1.

111. Conly JM, Stein K. The production of menaquinones (vitamin K2) by intestinal bacteria and their role in maintaining coagulation homeostasis. Prog Food Nutr Sci 1992; 16 (4):. 307-43. https://www.ncbi.nlm.nih.gov/pubmed/1492156

112. Bonnar J. Coagulation effects of oral contraception. Am J Obstet Gynecol. 1987; 157 (4 Pt 2): 1042-8. https://www.ncbi.nlm.nih.gov/pubmed/2960241

113. Link: https://www.ncbi.nlm.nih.gov/pubmed/?term=vitamin+D3+%2B+Depression

114. Spedding S. Vitamin D and Depression: A Systematic Review and Meta-Analysis Comparing Biological Studies With and without Flaws. Nutrients.2014; 6 (4): 1501-1518. doi: 10.3390 / nu6041501. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011048/

115. Spedding S. Vitamin D and Depression: Vitamin D and Depression: A Systematic Review and Meta-Analysis Comparing Studies with and without Biological Flaws. Nutrients.2014; 6 (4): 1501-1518. doi: 10.3390 / nu6041501. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011048/

116. Sartori SB N Whittle, Hetzenauer A Singewald N. Magnesium deficiency induces anxiety axis and HPA dysregulation: modulation by therapeutic drug treatment. Neuropharmacology. 2012; 62 (1): 304-12. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198864/

117. Syed I, M Wasay, Awan S. Treating Vitamin B12 Supplementation in Major Depressive Disorder: A Randomized Controlled Trial. The Open Neurology Journal. 2013; 7: 44-48. doi: 10.2174 / 1874205X01307010044. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856388/

118. Khoraminya N-Tehrani Doost M, S Jazayeri Hosseini A Djazayery A. Therapeutic effects of vitamin D therapy adjunctive to the fluoxetine in Patients with major depressive disorder. Aust NZJ Psychiatry. 2013; 47 (3): 271-5. https://www.ncbi.nlm.nih.gov/pubmed/23093054

119. Gloth FM Alam W, Hollis B. Vitamin D vs. broad spectrum phototherapy in the treatment of seasonal affective disorder. J Nutr Health Aging. 1999; 3 (1): 5-7. https://www.ncbi.nlm.nih.gov/pubmed/10888476

120. Gancheva SM, Zhelyazkova-Savova MD. Vitamin K2 Improves Anxiety and Depression but not Cognition in Rats with Metabolic Syndrome: The Role of Blood Glucose ?. Folia Med (Plovdiv). 2016; 58 (4): 264-272. https://www.ncbi.nlm.nih.gov/pubmed/28068285

121. An analogy popularized by autistic author Temple Grandin

122. Jia F, B Wang, Shan L, Xu Z, WG Staal, L. Du Core Symptoms of Vitamin D autism improved after supplementation. Pediatrics. 2015; 135 (1): e196-8. https://www.ncbi.nlm.nih.gov/pubmed/25511123

123. Cannell JJ. Vitamin D and autism, what's new ?. Rev Endocr Metab Disord. 2017; 18 (2): 183-193. https://www.ncbi.nlm.nih.gov/pubmed/28217829

124. Cannell JJ, Grant WB. What is the role of Vitamin D in autism ?. Dermatoendocrinol. 2013; 5 (1): 199-204. https://www.ncbi.nlm.nih.gov/pubmed/24494055

125. Article: https://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0024869/

126. Stubbs G, Henley K, Green J. Autism: Will vitamin D supplementation during pregnancy and early childhood reduces the recurrence rate of autism in newborn siblings ?. Med Hypotheses. 2016; 88: 74-8. https://www.ncbi.nlm.nih.gov/pubmed/26880644

127. Saad K, Abdel-Rahman AA, Elserogy YM, et al. Vitamin D status in autism spectrum disorders and the efficacy of vitamin D supplementation in autistic children. Nutr Neurosci. 2016: 19 (8): 346-351. https://www.ncbi.nlm.nih.gov/pubmed/25876214

128. Link: www.vitamindcouncil.org

129. Cannell JJ. Autism and vitamin D. Med Hypotheses. 2008; 70 (4): 750-9. https://www.ncbi.nlm.nih.gov/pubmed/17920208

130. Cannell JJ. Autism, will vitamin D treat core symptoms ?. Med Hypotheses. 2013; 81 (2): 195-8. https://www.ncbi.nlm.nih.gov/pubmed/23725905

131. Spedding S. Vitamin D and Depression: A Systematic Review and Meta-Analysis Comparing Studies with and without Biological Flaws. Nutrients. 2014; 6 (4): 1501-1518. doi: 10.3390 / nu6041501. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011048/

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15. Holick MF, Chen TC. Vitamin D deficiency: a worldwide problem with health consequences. Am J Clin Nutr. 2008;87(4):1080S-6S. https://www.ncbi.nlm.nih.gov/pubmed/18400738

16. Naeem Z. Vitamin D Deficiency- An Ignored Epidemic. International Journal of Health Sciences. 2010;4(1):V-VI. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068797/

17. Eles até deram um nome à ciência de dar nomes, a onomatologia.

18. Christakos S, Ajibade DV, Dhawan P, Fechner AJ, Mady LJ. Vitamin D: Metabolism. Endocrinology and metabolism clinics of North America. 2010;39(2):243-253. doi:10.1016/j.ecl.2010.02.002. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879391/

19. Às vezes os cientistas gostam de complicar muito as coisas, por isso cada um desses quatro químicos é também conhecido por muitos outros nomes diferentes. Não precisamos de os memorizar, mas se o leitor quiser, o diagrama 2 nos ajuda a desfazer qualquer confusão.

20. A estimulação do PTH também causaria um aumento de cálcio no sangue através da ativação natural de vitamina D que o PTH promove nos rins mas muito menor do que o que ocorre quando se suplementa diretamente com doses altas de vitamina D.

21. Artigo: https://www.nationalmssociety.org/What-is-MS/MS-FAQ-s#question-Is-MS-fatal

22. Video: https://www.youtube.com/watch?v=7OzP77HtR0Q a partir dos 2 minutos e 40 segundos

23. Video: http://sic.sapo.pt/Programas/altadefinicao/videos/2017-03-19-Alta-Definicao-com-Manuel-Pinto-Coelho

24. Video: http://sic.sapo.pt/Programas/altadefinicao/videos/2015-05-23-Bernardo-Pinto-Coelho-em-Alta-Definicao

25. Video: https://www.youtube.com/watch?v=hOfO29rL-gI

26. Artigo: http://www.auburn.edu/academic/forestry_wildlife/fire/combustion.htm

27. Artigo: https://www.publico.pt/1999/10/02/jornal/nasa-enganouse-nas-contas-124417

28. Armas LA, Hollis BW, Heaney RP. Vitamin D2 is much less effective than vitamin D3 in humans. J Clin Endocrinol Metab. 2004;89(11):5387-91. https://www.ncbi.nlm.nih.gov/pubmed/15531486

29. Documento: http://portal.anvisa.gov/documents/33916/389979/Rotulagem Nutricional Obrigatória Manual de Orientação às Indústrias de Alimentos/ae72b30a-07af-42e2-8b76-10ff96b64ca4, página 34.

30. Tripkovic L, Lambert H, Hart K, et al. Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysis. The American Journal of Clinical Nutrition. 2012;95(6):1357-1364. doi:10.3945/ajcn.111.031070. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349454/

31. Keegan R-JH, Lu Z, Bogusz JM, Williams JE, Holick MF. Photobiology of vitamin D in mushrooms and its bioavailability in humans. Dermato-endocrinology. 2013;5(1):165-176. doi:10.4161/derm.23321. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897585/

32. Artigo: https://dietarysupplementdatabase.usda.nih.gov/ingredient_calculator/equation.php

33. Domene, AC. Multiple Sclerosis and (lots of) Vitamin D: My Eight-Year Treatment with The Coimbra Protocol for Autoimmune Diseases. Amazon Digital Services LLC. 2016. Página 16.

34. Goldenberg MM. Multiple Sclerosis Review. Pharmacy and Therapeutics. 2012;37(3):175-184. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351877/

35. Sieper J, Braun J, Rudwaleit M, Boonen A, Zink A. Ankylosing spondylitis: an overview. Annals of the Rheumatic Diseases. 2002;61(Suppl 3):iii8-iii18. doi:10.1136/ard.61.suppl_3.iii8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1766729/

36. Hathcock JN, Shao A, Vieth R, Heaney R. Risk assessment for vitamin D. Am J Clin Nutr. 2007;85(1):6-18. https://www.ncbi.nlm.nih.gov/pubmed/17209171

37. Artigo: https://www.vitamindcouncil.org/about-vitamin-d/am-i-getting-too-much-vitamin-d/

38. Vieth R. Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety. Am J Clin Nutr. 1999;69(5):842-56. https://www.ncbi.nlm.nih.gov/pubmed/10232622

39. Artigo: https://www.vitamindcouncil.org/about-vitamin-d/how-do-i-get-the-vitamin-d-my-body-needs/

40. Matsuoka LY, Ide L, Wortsman J, Maclaughlin JA, Holick MF. Sunscreens suppress cutaneous vitamin D3 synthesis. J Clin Endocrinol Metab. 1987;64(6):1165-8. https://www.ncbi.nlm.nih.gov/pubmed/3033008

41. Holick M. “Photobiology of Vitamin D” Vitamin D: Second Edition, 2005.

42. Artigo: https://www.vitamindcouncil.org/about-vitamin-d/how-do-i-get-the-vitamin-d-my-body-needs/

43. Informação detalhada sobre as quantidades de vitamina D3 e D2 presentes em diversos alimentos estão disponíveis no apêndice A.

44. Artigo: http://www.thisisms.com/forum/coimbra-high-dose-vitamin-d-protocol-f57/topic27182.html

45. Artigo: https://www.livestrong.com/article/537905-can-drinking-too-much-water-cause-low-potassium/

46. Balcı AK, Koksal O, Kose A, et al. General characteristics of patients with electrolyte imbalance admitted to emergency department. World Journal of Emergency Medicine. 2013;4(2):113-116. doi:10.5847/wjem.j.issn.1920-8642.2013.02.005. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129840/

47. Weglicki W, Quamme G, Tucker K, Haigney M, Resnick L. Potassium, magnesium, and electrolyte imbalance and complications in disease management. Clin Exp Hypertens. 2005;27(1):95-112. https://www.ncbi.nlm.nih.gov/pubmed/15773233

48. Ritter CS, Armbrecht HJ, Slatopolsky E, Brown AJ. 25-Hydroxyvitamin D(3) suppresses PTH synthesis and secretion by bovine parathyroid cells. Kidney Int. 2006;70(4):654-9. https://www.ncbi.nlm.nih.gov/pubmed/16807549

49. Friedl C, Zitt E. Vitamin D prohormone in the treatment of secondary hyperparathyroidism in patients with chronic kidney disease. Int J Nephrol Renovasc Dis. 2017;10:109-122. https://www.ncbi.nlm.nih.gov/pubmed/28546765

50. Lotito A, Teramoto M, Cheung M, Becker K, Sukumar D. Serum Parathyroid Hormone Responses to Vitamin D Supplementation in Overweight/Obese Adults: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Nutrients. 2017;9(3):241. doi:10.3390/nu9030241. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372904/

51. Abrams SA, Hawthorne KM, Chen Z. Supplementation with 1000 IU vitamin D/d leads to parathyroid hormone suppression, but not increased fractional calcium absorption, in 4-8-y-old children: a double-blind randomized controlled trial. Am J Clin Nutr. 2013;97(1):217-23. https://www.ncbi.nlm.nih.gov/pubmed/23151536

52. Tardelli VS, Lago MPPD, Silveira DXD, Fidalgo TM. Vitamin D and alcohol: A review of the current literature. Psychiatry Res. 2017;248:83-86. http://www.psy-journal.com/article/S0165-1781(16)30706-5/fulltext

53. Epstein M. Alcohol's impact on kidney function. Alcohol Health Res World. 1997;21(1):84-92.Epstein M. Alcohol's impact on kidney function. Alcohol Health Res World. 1997;21(1):84-92. https://www.ncbi.nlm.nih.gov/pubmed/15706766

54. Sampson HW. Alcohol's harmful effects on bone. Alcohol Health Res World. 1998;22(3):190-4. https://www.ncbi.nlm.nih.gov/pubmed/15706795

55. Szabo G, Mandrekar P. Focus On: Alcohol and the Liver. Alcohol Research & Health. 2010;33(1-2):87-96. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3860520/

56. Zahr NM, Pfefferbaum A. Alcohol's Effects on the Brain: Neuroimaging Results in Humans and Animal Models. Alcohol Res. 2017;38(2):183-206. https://www.ncbi.nlm.nih.gov/pubmed/28988573

57. Tada A. Psychological effects of exercise on community-dwelling older adults. Clin Interv Aging. 2018;13:271-276. https://www.ncbi.nlm.nih.gov/pubmed/29483773

58. Blumenthal JA, Babyak MA, Moore KA, et al. Effects of exercise training on older patients with major depression. Arch Intern Med. 1999;159(19):2349-56. https://www.ncbi.nlm.nih.gov/pubmed/10547175

59. Lamina S, Agbanusi E, Nwacha RC. Effects of Aerobic Exercise in the Management of Erectile Dysfunction: A Meta Analysis Study on Randomized Controlled Trials. Ethiopian Journal of Health Sciences. 2011;21(3):195-201. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275865/

60. Silva AB, Sousa N, Azevedo LF, Martins C. Physical activity and exercise for erectile dysfunction: systematic review and meta-analysis. Br J Sports Med. 2017;51(19):1419-1424. https://www.ncbi.nlm.nih.gov/pubmed/27707739

61. Buchner DM, Beresford SA, Larson EB, Lacroix AZ, Wagner EH. Effects of physical activity on health status in older adults. II. Intervention studies. Annu Rev Public Health. 1992;13:469-88. https://www.ncbi.nlm.nih.gov/pubmed/1599599/

62. Mcmillan LB, Zengin A, Ebeling PR, Scott D. Prescribing Physical Activity for the Prevention and Treatment of Osteoporosis in Older Adults. Healthcare (Basel). 2017;5(4) https://www.ncbi.nlm.nih.gov/pubmed/29113119

63. Hinton PS, Nigh P, Thyfault J. Effectiveness of resistance training or jumping-exercise to increase bone mineral density in men with low bone mass: A 12-month randomized, clinical trial. Bone. 2015;79:203-12. https://www.ncbi.nlm.nih.gov/pubmed/26092649

64. Zhao R, Zhao M, Zhang L. Efficiency of jumping exercise in improving bone mineral density among premenopausal women: a meta-analysis. Sports Med. 2014;44(10):1393-402. https://www.ncbi.nlm.nih.gov/pubmed/24981245

65. Paillard T. [Exercise and bone mineral density in old subjects: theorical and practical implications]. Geriatr Psychol Neuropsychiatr Vieil. 2014;12(3):267-73. https://www.ncbi.nlm.nih.gov/pubmed/25245313

66. Watson SL, Weeks BK, Weis LJ, Horan SA, Beck BR. Heavy resistance training is safe and improves bone, function, and stature in postmenopausal women with low to very low bone mass: novel early findings from the LIFTMOR trial. Osteoporos Int. 2015;26(12):2889-94. https://www.ncbi.nlm.nih.gov/pubmed/26243363/

67. Brot C, Jorgensen NR, Sorensen OH. The influence of smoking on vitamin D status and calcium metabolism. Eur J Clin Nutr. 1999;53(12):920-6. https://www.ncbi.nlm.nih.gov/pubmed/10602348

68. Ren W, Gu Y, Zhu L, et al. The effect of cigarette smoking on vitamin D level and depression in male patients with acute ischemic stroke. Compr Psychiatry. 2016;65:9-14. https://www.ncbi.nlm.nih.gov/pubmed/26773985

69. Coelho MP. Chegar novo a velho, medicina do futuro. 2016. Página 134

70. Yagnik D, Serafin V, J shah A. Antimicrobial activity of apple cider vinegar against Escherichia coli, Staphylococcus aureus and Candida albicans; downregulating cytokine and microbial protein expression. Sci Rep. 2018;8(1):1732. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788933/

71. Trill J, Simpson C, Webley F, et al. Uva-ursi extract and ibuprofen as alternative treatments of adult female urinary tract infection (ATAFUTI): study protocol for a randomised controlled trial. Trials. 2017;18(1):421. https://www.ncbi.nlm.nih.gov/pubmed/28886751

72. Hisano M, Bruschini H, Nicodemo AC, Srougi M. Cranberries and lower urinary tract infection prevention. Clinics. 2012;67(6):661-667. doi:10.6061/clinics/2012(06)18. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370320/

73. Francino MP. Antibiotics and the Human Gut Microbiome: Dysbioses and Accumulation of Resistances. Frontiers in Microbiology. 2015;6:1543. doi:10.3389/fmicb.2015.01543. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709861/

74. Coimbra CG, Junqueira VB. High doses of riboflavin and the elimination of dietary red meat promote the recovery of some motor functions in Parkinson's disease patients. Braz J Med Biol Res. 2003;36(10):1409-17. https://www.ncbi.nlm.nih.gov/pubmed/14502375

75. Anderson BB, Scattoni M, Perry GM, et al. Is the flavin-deficient red blood cell common in Maremma, Italy, an important defense against malaria in this area? American Journal of Human Genetics. 1994;55(5):975-980. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1918332/

76. Marashly ET, Bohlega SA. Riboflavin Has Neuroprotective Potential: Focus on Parkinson's Disease and Migraine. Front Neurol. 2017;8:333. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517396/

77. Adiloğlu AK, Gönülateş N, Işler M, Senol A. [The effect of kefir consumption on human immune system: a cytokine study]. Mikrobiyol Bul. 2013;47(2):273-81. https://www.ncbi.nlm.nih.gov/pubmed/23621727

78. Maresz K. Proper Calcium Use: Vitamin K2 as a Promoter of Bone and Cardiovascular Health. Integrative Medicine: A Clinician’s Journal. 2015;14(1):34-39. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566462/

79. Bowles JT. The Miraculous Results of Extremely High Doses of the Sunshine Hormone Vitamin D3 My Experiment with Huge Doses of D3 from 25,000 to 50,000 to 100,000 Iu a Day Over a 1 Year Period. CreateSpace; 2013.

80. Coelho MP. Chegar novo a velho, medicina do futuro. 2016.

81. Crescenti A, Puiggròs F, Colomé A, et al. [Antiurolithiasic effect of a plant mixture of Herniaria glabra, Agropyron repens, Equisetum arvense and Sambucus nigra (Herbensurina®) in the prevention of experimentally induced nephrolithiasis in rats]. Arch Esp Urol. 2015;68(10):739-49. https://www.ncbi.nlm.nih.gov/pubmed/26634575

82. Composto por: (1) Herniaria ou erva-turca (Herniaria glabra L.) (Planta inteira) 1 grama por saqueta. (2) Grama das farmácias (Agropyron repens (L.) P. Beauv.) (rizoma) 0,25 gramas por saqueta. (3) Cavalinha (Equisetum arvense L.) (caules estéreis) 0.15 gramas por saqueta. (4) Flor de sabugueiro (Sambucus nigra L.) (flores) 0.1 gramas por saqueta.

83. Comunicação pessoal durante uma consulta.

84. Bonnar J. Coagulation effects of oral contraception. Am J Obstet Gynecol. 1987;157(4 Pt 2):1042-8. https://www.ncbi.nlm.nih.gov/pubmed/2960241

85. Artigo: https://www.sharecare.com/health/blood-basics/how-many-white-blood-cells

86. Artigo: https://www.healthline.com/health/how-much-blood-in-human-body

87. Artigo: https://www.vitamindcouncil.org/gene-expression-and-vitamin-d-whats-the-link/

88. Hossein-nezhad A, Spira A, Holick MF. Influence of Vitamin D Status and Vitamin D3 Supplementation on Genome Wide Expression of White Blood Cells: A Randomized Double-Blind Clinical Trial. Campbell M, ed. PLoS ONE. 2013;8(3):e58725. doi:10.1371/journal.pone.0058725.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604145/

89. Prietl B, Treiber G, Pieber TR, Amrein K. Vitamin D and Immune Function. Nutrients. 2013;5(7):2502-2521. doi:10.3390/nu5072502. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738984/

90. Chambers ES, Hawrylowicz CM. The impact of vitamin D on regulatory T cells. Curr Allergy Asthma Rep. 2011;11(1):29-36. https://www.ncbi.nlm.nih.gov/pubmed/21104171

91. Sigmundsdottir H, Pan J, Debes GF, et al. DCs metabolize sunlight-induced vitamin D3 to 'program' T cell attraction to the epidermal chemokine CCL27. Nat Immunol. 2007;8(3):285-93. https://www.ncbi.nlm.nih.gov/pubmed/17259988

92. Pillay J, Den braber I, Vrisekoop N, et al. In vivo labeling with 2H2O reveals a human neutrophil lifespan of 5.4 days. Blood. 2010;116(4):625-7. http://www.bloodjournal.org/content/116/4/625?ijkey=1a3c177de0b39ae4c1ec8754e0b3c71cd72451d5

93. Cvetanovich GL, Hafler DA. Human Regulatory T Cells in Autoimmune Diseases. Current opinion in immunology. 2010;22(6):753-760. doi:10.1016/j.coi.2010.08.012. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997859/

94. Lis K, Kuzawińska O, Bałkowiec-Iskra E. Tumor necrosis factor inhibitors – state of knowledge. Archives of Medical Science : AMS. 2014;10(6):1175-1185. doi:10.5114/aoms.2014.47827. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296073/

95. Artigo: http://www.news.med.br/p/saude/222530/oms+divulga+as+dez+principais+causas+de+morte+no+mundo.htm

96. Sharma RK, Sharma RK, Voelker DJ, et al. Cardiac risk stratification: Role of the coronary calcium score. Vascular Health and Risk Management. 2010;6:603-611. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922321/

97. Maresz K. Proper Calcium Use: Vitamin K2 as a Promoter of Bone and Cardiovascular Health. Integrative Medicine: A Clinician’s Journal. 2015;14(1):34-39. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566462/

98. Rheaume-Bleue K. Vitamin K2 and the Calcium Paradox: How a Little-Known Vitamin Could Save Your Life. Harper; 2013. Página 39

99. Lhermusier T, Chap H, Payrastre B. Platelet membrane phospholipid asymmetry: from the characterization of a scramblase activity to the identification of an essential protein mutated in Scott syndrome. J Thromb Haemost. 2011;9(10):1883-91. https://www.ncbi.nlm.nih.gov/pubmed/21958383

100. Haque JA, McDonald MG, Kulman JD, Rettie AE. A cellular system for quantitation of vitamin K cycle activity: structure-activity effects on vitamin K antagonism by warfarin metabolites. Blood. 2014;123(4):582-589. doi:10.1182/blood-2013-05-505123. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901071/

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102. É digno de nota que leite e seus derivados, como o queijo, estão contraindicados num protocolo com doses elevadas de vitamina D devido a seu alto teor em cálcio

103. Tsukamoto Y, Ichise H, Kakuda H, Yamaguchi M. Intake of fermented soybean (natto) increases circulating vitamin K2 (menaquinone-7) and gamma-carboxylated osteocalcin concentration in normal individuals. J Bone Miner Metab. 2000;18(4):216-22. https://www.ncbi.nlm.nih.gov/pubmed/10874601

104. Artigo: https://pubchem.ncbi.nlm.nih.gov/compound/octane

105. Artigo: https://pubchem.ncbi.nlm.nih.gov/compound/ethane

106. Artigo: https://pubchem.ncbi.nlm.nih.gov/compound/benzene

107. Sato T, Schurgers LJ, Uenishi K. Comparison of menaquinone-4 and menaquinone-7 bioavailability in healthy women. Nutr J. 2012;11:93. https://www.ncbi.nlm.nih.gov/pubmed/23140417

108. Uma vitamina fictícia.

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110. Bonnar J. Coagulation effects of oral contraception. Am J Obstet Gynecol. 1987;157(4 Pt 2):1042-8. https://www.ncbi.nlm.nih.gov/pubmed/2960241

111. Link: https://www.ncbi.nlm.nih.gov/pubmed/?term=vitamin+D3+%2B+Depression

112. Spedding S. Vitamin D and Depression: A Systematic Review and Meta-Analysis Comparing Studies with and without Biological Flaws. Nutrients. 2014;6(4):1501-1518. doi:10.3390/nu6041501. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011048/

113. Spedding S. Vitamin D and Depression: A Systematic Review and Meta-Analysis Comparing Studies with and without Biological Flaws. Nutrients. 2014;6(4):1501-1518. doi:10.3390/nu6041501. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011048/

114. Sartori SB, Whittle N, Hetzenauer A, Singewald N. Magnesium deficiency induces anxiety and HPA axis dysregulation: modulation by therapeutic drug treatment. Neuropharmacology. 2012;62(1):304-12. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198864/

115. Syed EU, Wasay M, Awan S. Vitamin B12 Supplementation in Treating Major Depressive Disorder: A Randomized Controlled Trial. The Open Neurology Journal. 2013;7:44-48. doi:10.2174/1874205X01307010044. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856388/

116. Khoraminya N, Tehrani-doost M, Jazayeri S, Hosseini A, Djazayery A. Therapeutic effects of vitamin D as adjunctive therapy to fluoxetine in patients with major depressive disorder. Aust N Z J Psychiatry. 2013;47(3):271-5. https://www.ncbi.nlm.nih.gov/pubmed/23093054

117. Gloth FM, Alam W, Hollis B. Vitamin D vs broad spectrum phototherapy in the treatment of seasonal affective disorder. J Nutr Health Aging. 1999;3(1):5-7. https://www.ncbi.nlm.nih.gov/pubmed/10888476

118. Gancheva SM, Zhelyazkova-savova MD. Vitamin K2 Improves Anxiety and Depression but not Cognition in Rats with Metabolic Syndrome: a Role of Blood Glucose?. Folia Med (Plovdiv). 2016;58(4):264-272. https://www.ncbi.nlm.nih.gov/pubmed/28068285

119. Jia F, Wang B, Shan L, Xu Z, Staal WG, Du L. Core symptoms of autism improved after vitamin D supplementation. Pediatrics. 2015;135(1):e196-8. https://www.ncbi.nlm.nih.gov/pubmed/25511123

120. https://www.ncbi.nlm.nih.gov/pubmed/25876214

121. Feng J, Shan L, Du L, et al. Clinical improvement following vitamin D3 supplementation in Autism Spectrum Disorder. Nutr Neurosci. 2016; https://www.ncbi.nlm.nih.gov/pubmed/26783092

122. Cannell JJ. Vitamin D and autism, what's new?. Rev Endocr Metab Disord. 2017;18(2):183-193. https://www.ncbi.nlm.nih.gov/pubmed/28217829

123. Cannell JJ, Grant WB. What is the role of vitamin D in autism?. Dermatoendocrinol. 2013;5(1):199-204. https://www.ncbi.nlm.nih.gov/pubmed/24494055

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126. Artigo: https://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0024869/

127. Stubbs G, Henley K, Green J. Autism: Will vitamin D supplementation during pregnancy and early childhood reduce the recurrence rate of autism in newborn siblings?. Med Hypotheses. 2016;88:74-8. https://www.ncbi.nlm.nih.gov/pubmed/26880644

128. Saad K, Abdel-rahman AA, Elserogy YM, et al. Vitamin D status in autism spectrum disorders and the efficacy of vitamin D supplementation in autistic children. Nutr Neurosci. 2016;19(8):346-351. https://www.ncbi.nlm.nih.gov/pubmed/25876214

129. Ligação: www.vitamindcouncil.org

130. Cannell JJ. Autism and vitamin D. Med Hypotheses. 2008;70(4):750-9. https://www.ncbi.nlm.nih.gov/pubmed/17920208

131. Cannell JJ. Autism, will vitamin D treat core symptoms?. Med Hypotheses. 2013;81(2):195-8. https://www.ncbi.nlm.nih.gov/pubmed/23725905

132. Spedding S. Vitamin D and Depression: A Systematic Review and Meta-Analysis Comparing Studies with and without Biological Flaws. Nutrients. 2014;6(4):1501-1518. doi:10.3390/nu6041501. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011048/

133. Artigo: https://www.medscape.com/viewarticle/551998

134. Fouad YA, Aanei C. Revisiting the hallmarks of cancer. American Journal of Cancer Research. 2017;7(5):1016-1036. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446472/

135. Chakraborti CK. Vitamin D as a promising anticancer agent. Indian Journal of Pharmacology. 2011;43(2):113-120. doi:10.4103/0253-7613.77335. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081446/

136. Lowe LC, Guy M, Mansi JL, et al. Plasma 25-hydroxy vitamin D concentrations, vitamin D receptor genotype and breast cancer risk in a UK Caucasian population. Eur J Cancer. 2005;41(8):1164-9. https://www.ncbi.nlm.nih.gov/pubmed/15911240

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221. Artigo: https://labtestsonline.org.br/tests/amonia

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223. Artigo: https://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/9265

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237. Artigo: https://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/61695

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241. Artigo: http://www.hermespardini.com.br/scripts/mgwms32.dll?MGWLPN=HPHOSTBS&App=HELPE&EXAME=S%7C%7CCTX

242. Se você quer uma mnemónica simples para nunca confundir os dois, imagine que o osteoblasto sopra (do inglês “blasts”) partículas de tecido ósseo para formar osso, igual a uma pistola de tinta. Ao mesmo tempo imagine que o osteoclasto está com um machado cortando osso (do inglês “clash”). Então, osteoBLASTo sopra osso e osteoCLASto tira o osso.

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248. Composto por: (1) Herniaria ou erva-turca (Herniaria glabra L.) (Planta inteira) 1 grama por saqueta. (2) Grama das farmácias (Agropyron repens (L.) P. Beauv.) (rizoma) 0,25 gramas por saqueta. (3) Cavalinha (Equisetum arvense L.) (caules estéreis) 0.15 gramas por saqueta. (4) Flor de sabugueiro (Sambucus nigra L.) (flores) 0.1 gramas por saqueta.

249. Artigo: http://www.alvaro.com.br/laboratorio/menu-exames/FOSFU

250. Artigo: http://www.alvaro.com.br/laboratorio/menu-exames/SODIO

251. Artigo: http://www.alvaro.com.br/laboratorio/menu-exames/K

252. Artigo: http://www.alvaro.com.br/laboratorio/menu-exames/CLORO

253. Artigo: http://www.alvaro.com.br/laboratorio/menu-exames/MGS

254. Artigo: http://www.alvaro.com.br/laboratorio/menu-exames/BICARS

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